Changes in energy metabolism and X-ray sensitivity in murine tumours by the nitric oxide donor SIN-1.

The effect of the nitric oxide (NO) donor SIN-1 on energy metabolism was examined in three murine transplantable tumours in vivo using 31P MRS. SIN-1 at 2 mg kg-1 i.v. reduced Pi/total by 40-50% in SCCVII/Ha and KHT tumours within 5 min of injection, returning to control levels by 20 min. However, t...

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Main Authors: Wood, P. J., Sansom, J. M., Stratford, I. J., Adams, G. E., Szabo, C., Thiemermann, C., Vane, J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149982/
https://ncbi.nlm.nih.gov/pubmed/8763875
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