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The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells.

Loss of DNA mismatch repair is a common finding in hereditary non-polyposis colon cancer as well as in many types of sporadic human tumours. We compared the effect of loss of DNA mismatch repair on drug sensitivity as measured by a clonogenic assay with its effect on the ability of the same drug to...

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Bibliographische Detailangaben
Hauptverfasser: Fink, D., Nebel, S., Norris, P. S., Aebi, S., Kim, H. K., Haas, M., Howell, S. B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149976/
https://ncbi.nlm.nih.gov/pubmed/9514047
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