Suppression by pravastatin, an inhibitor of p21ras isoprenylation, of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.

The effect of pravastatin, an inhibitor of p21ras isoprenylation, on hepatocarcinogenesis induced by N-nitrosomorpholine and on p21ras isoprenylation were investigated in male Sprague-Dawley rats. Rats received i.p. injections of pravastatin (10 and 20 mg kg(-1) body weight) every other day and, fro...

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Библиографические подробности
Главные авторы: Tatsuta, M., Iishi, H., Baba, M., Iseki, K., Yano, H., Uehara, H., Yamamoto, R., Nakaizumi, A.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1998
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149937/
https://ncbi.nlm.nih.gov/pubmed/9484815
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