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Inhibitors of aromatase prevent degradation of the enzyme in cultured human tumour cells.

The effects of two steroidal (4-hydroxyandrostenedione and atamestane) and three non-steroidal (fadrozole, vorozole and pentrozole) aromatase inhibitors on the levels of aromatase mRNA and protein were examined using cultured JEG-3 and HepG2 cells. Immunocytochemical studies demonstrated increased q...

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Autori principali: Harada, N., Hatano, O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149917/
https://ncbi.nlm.nih.gov/pubmed/9484813
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