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Mutations in the rpoH (htpR) gene of Escherichia coli K-12 phenotypically suppress a temperature-sensitive mutant defective in the sigma 70 subunit of RNA polymerase.

Escherichia coli K-12 strain 285c contains a mutation in rpoD, the gene encoding the sigma subunit of RNA polymerase. The 70-kilodalton sigma polypeptide encoded by this allele is unstable, and this instability leads to temperature-sensitive growth. We describe the isolation and characterization of...

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Udgivet i:J Bacteriol
Principais autores: Grossman, A D, Zhou, Y N, Gross, C, Heilig, J, Christie, G E, Calendar, R
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC214988/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3882672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.161.3.939-943.1985
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