Alternative models for early onset of childhood leukaemia.

This paper considers theoretical models for early-onset childhood leukaemia. The major focus of attention is the two-hit mutational model. A simple mathematical representation is used to explore mechanisms which might lead to onset of leukaemia at an unusually early age. Two such mechanisms are cons...

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Autori principali: Wheldon, T. E., Mairs, R. J., Barrett, A., Wheldon, E. G., Gibson, B. E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1992
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149658/
https://ncbi.nlm.nih.gov/pubmed/1503920
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