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Effect of radiation on cis-dichlorodiammineplatinum (II) and DNA in aqueous solution.
The radiolysis of cis-dichlorodiammineplatinum (II) (cis-PDD) was studied in order to better understand the mechanisms by which it acts as a radiation sensitizer. The Pt(I) intermediate formed by e- aq reduction of cis-PDD loses both chlorides rapidly, interacts with O2 to form a Pt-oxygen adduct, r...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
1978
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2149397/ https://ncbi.nlm.nih.gov/pubmed/277227 |
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