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The effect of the radiosensitizer misonidazole on motor nerve conduction velocity in the mouse.

The clinical use of misonidazole as a hypoxic cell radiosensitizer is at present limited by its neurotoxicity at high doses (Urtasun et al., 1977; Dische et al., 1977). An in vivo neurological end point, viz. measurement of nerve conduction velocity, has been developed to examine sensitizer action....

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Autors principals: Hirst, D. G., Vojnovic, B., Stratford, I. J., Travis, E. L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1978
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149369/
https://ncbi.nlm.nih.gov/pubmed/277237
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