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Dynamics of the Genome during Early Xenopus laevis Development: Karyomeres As Independent Units of Replication

During Xenopus laevis early development, the genome is replicated in less than 15 min every 30 min. We show that during this period, DNA replication proceeds in an atypical manner. Chromosomes become surrounded by a nuclear membrane lamina forming micronuclei or karyomeres. This genomic organization...

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Bibliografiske detaljer
Main Authors: Lemaitre, Jean-Marc, Géraud, Gérard, Méchali, Marcel
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149347/
https://ncbi.nlm.nih.gov/pubmed/9732278
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