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The response of a human tumour xenograft to chemotherapy: intrinsic variation between tumours and its significance in planning experiments.

The HT29R human colon adenocarcinoma cell line has been used to investigate the problem of inter-tumour variability in the xenograft system and how this may affect the planning of chemotherapy experiments. Subcutaneous inoculation of 10(6) in vitro cells into immuno-suppressed mice yielded an 80% ta...

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Autori principali: Warenius, H. M., Freedman, L. S., Bleehen, N. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1980
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149238/
https://ncbi.nlm.nih.gov/pubmed/6932916
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