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Response of an in vivo-in vitro tumour to X-rays and cytotoxic drugs: effect of tumour disaggregation method on cell survival.

EMT-6/UW tumours were treated in vivo with X-rays, cyclophosphamide, or bleomycin. Cell survival was assayed in vitro following tumour disaggregation with trypsin or an enzyme cocktail (EC) consisting of pronase, collagenase and DNase which gives a 10-20 x higher cell yield. Surviving fraction was l...

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Detalhes bibliográficos
Main Authors: Rasey, J. S., Nelson, N. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149195/
https://ncbi.nlm.nih.gov/pubmed/6158976
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