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Antinociceptive action of tricyclic antidepressant drugs in the rat.
The antinociceptive effects of controlled release amitriptyline, desipramine, and placebo pellets were studied over 3 weeks using the hot plate method in 45 rats. Animals treated with desipramine at total doses of 50 mg (8 mg/kg/day) and 100 mg (16 mg/kg/day) displayed analgesia for up to 48 hours c...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Dental Society of Anesthesiology
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2148668/ https://ncbi.nlm.nih.gov/pubmed/2096740 |
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