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Competitive release and facilitation of drug-resistant parasites after therapeutic chemotherapy in a rodent malaria model

Malaria infections frequently consist of mixtures of drug-resistant and drug-sensitive parasites. If crowding occurs, where clonal population densities are suppressed by the presence of coinfecting clones, removal of susceptible clones by drug treatment could allow resistant clones to expand into th...

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Detalhes bibliográficos
Main Authors: Wargo, Andrew R., Huijben, Silvie, de Roode, Jacobus C., Shepherd, James, Read, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148397/
https://ncbi.nlm.nih.gov/pubmed/18056635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707766104
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