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Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha

Isothiocyanates and phenolic antioxidants can prevent cancer through activation of Nrf2 (NF-E2 p45-related factor 2), a transcription factor that controls expression of cytoprotective genes through the antioxidant response element (ARE) enhancer. Using a human mammary MCF7-derived AREc32 reporter ce...

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Bibliografski detalji
Glavni autori: Wang, Xiu Jun, Hayes, John D., Henderson, Colin J., Wolf, C. Roland
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148333/
https://ncbi.nlm.nih.gov/pubmed/18048326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709483104
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