DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status

A complex combination of adult health-related disorders can originate from developmental events that occur in utero. The periconceptional period may also be programmable. We report on the effects of restricting the supply of specific B vitamins (i.e., B(12) and folate) and methionine, within normal...

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Hlavní autoři: Sinclair, Kevin D., Allegrucci, Cinzia, Singh, Ravinder, Gardner, David S., Sebastian, Sonia, Bispham, Jayson, Thurston, Alexandra, Huntley, John F., Rees, William D., Maloney, Christopher A., Lea, Richard G., Craigon, Jim, McEvoy, Tom G., Young, Lorraine E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148293/
https://ncbi.nlm.nih.gov/pubmed/18042717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707258104
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