Protein Tyrosine Phosphatase-PEST Regulates Focal Adhesion Disassembly, Migration, and Cytokinesis in Fibroblasts

In this article, we show that, in transfected COS-1 cells, protein tyrosine phosphatase (PTP)-PEST translocates to the membrane periphery following stimulation by the extracellular matrix protein fibronectin. When plated on fibronectin, PTP-PEST (−/−) fibroblasts display a strong defect in motility....

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Main Authors: Angers-Loustau, Alexandre, Côté, Jean-François, Charest, Alain, Dowbenko, Donald, Spencer, Susan, Lasky, Laurence A., Tremblay, Michel L.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1999
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148201/
https://ncbi.nlm.nih.gov/pubmed/10085298
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