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Specific Myosin Heavy Chain Mutations Suppress Troponin I Defects in Drosophila Muscles

We show that specific mutations in the head of the thick filament molecule myosin heavy chain prevent a degenerative muscle syndrome resulting from the hdp(2) mutation in the thin filament protein troponin I. One mutation deletes eight residues from the actin binding loop of myosin, while a second a...

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Détails bibliographiques
Auteurs principaux: Kronert, William A., Acebes, Angel, Ferrús, Alberto, Bernstein, Sanford I.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148188/
https://ncbi.nlm.nih.gov/pubmed/10085296
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