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Dynamic Localization of CLIP-170 to Microtubule Plus Ends Is Coupled to Microtubule Assembly

CLIP-170 is a cytoplasmic linker protein that localizes to plus ends of microtubules in vivo. In this study, we have characterized the microtubule-binding properties of CLIP-170, to understand the mechanism of its plus end targeting. We show that the NH(2)-terminal microtubule-interacting domain of...

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Bibliografiske detaljer
Main Authors: Diamantopoulos, Georgios S., Perez, Franck, Goodson, Holly V., Batelier, Gérard, Melki, Ronald, Kreis, Thomas E., Rickard, Janet E.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148115/
https://ncbi.nlm.nih.gov/pubmed/9885247
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