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T cells recognizing leukemic CD34(+) progenitor cells mediate the antileukemic effect of donor lymphocyte infusions for relapsed chronic myeloid leukemia after allogeneic stem cell transplantation

Adoptive immunotherapy with donor lymphocyte infusions (DLI) is an effective treatment for relapsed chronic myeloid leukemia (CML) after allogeneic stem cell transplantation. To identify the effector and target cell populations responsible for the elimination of the leukemic cells in vivo we develop...

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Auteurs principaux: Smit, Willem M., Rijnbeek, Marion, van Bergen, Cornelis A. M., Fibbe, Willem E., Willemze, Roel, Falkenburg, J. H. Frederik
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC21477/
https://ncbi.nlm.nih.gov/pubmed/9707616
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