Fas-independent death of activated CD4(+) T lymphocytes induced by CTLA-4 crosslinking
The CTLA-4 receptor is a critical inhibitory regulator of T cell proliferation and effector function. However, the mechanisms through which CTLA-4 modulates the activation of T cells remain uncertain. Initial studies, using activated human T cells, have suggested that CTLA-4 crosslinking may induce...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21465/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9707604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.17.10083 |
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