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Does secA mediate coupling between secretion and translation in Escherichia coli?

An amber mutation in the secA gene of Escherichia coli causes a pleiotropic decrease in the synthesis of secreted proteins, including maltose-binding protein (MBP) and alkaline phosphatase. Reversal of the inhibition of MBP synthesis in secA(Am) strains by signal sequence mutations in the malE gene...

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Detalhes bibliográficos
Main Authors: Strauch, K L, Kumamoto, C A, Beckwith, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC214633/
https://ncbi.nlm.nih.gov/pubmed/3009404
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