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The active site and substrates binding mode of malonyl-CoA synthetase determined by transferred nuclear Overhauser effect spectroscopy, site-directed mutagenesis, and comparative modeling studies.

The active sites and substrate bindings of Rhizobium trifolii molonyl-CoA synthetase (MCS) catalyzing the malonyl-CoA formation from malonate and CoA have been determined based on NMR spectroscopy, site-directed mutagenesis, and comparative modeling methods. The MCS-bound conformation of malonyl-CoA...

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Главные авторы: Jung, J. W., An, J. H., Na, K. B., Kim, Y. S., Lee, W.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144687/
https://ncbi.nlm.nih.gov/pubmed/10933494
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