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Peptide and metal ion-dependent association of isolated helix-loop-helix calcium binding domains: studies of thrombic fragments of calmodulin.

Calmodulin (CaM), the ubiquitous, eukaryotic, bilobal calcium-binding regulatory protein, has been cleaved by thrombin to create two fragments. TM1 (1-106) and TM2 (107-148). NMR and CD results indicate that TMI and TM2 can associate in the presence of Ca2+ to form a complex similar to native CaM, e...

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Bibliografiske detaljer
Main Authors: Brokx, R. D., Vogel, H. J.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144632/
https://ncbi.nlm.nih.gov/pubmed/10850806
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