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Characterization of an anti-Borrelia burgdorferi OspA conformational epitope by limited proteolysis of monoclonal antibody-bound antigen and mass spectrometric peptide mapping.

Lyme borreliosis is a multisystem disorder caused by the spirochete Borrelia burgdorferi that is transmitted to humans by the tick Ixodes dammini. The immune response against the 31 kDa OspA, which is one of the most abundant B. burgdorferi proteins, appears to be critical in preventing infection an...

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Detalhes bibliográficos
Main Authors: Legros, V., Jolivet-Reynaud, C., Battail-Poirot, N., Saint-Pierre, C., Forest, E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144631/
https://ncbi.nlm.nih.gov/pubmed/10850810
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