Characterization of a comparative model of the extracellular domain of the epidermal growth factor receptor.

The Epidermal Growth Factor (EGF) receptor is a tyrosine kinase that mediates the biological effects of ligands such as EGF and transforming growth factor alpha. An understanding of the molecular basis of its action has been hindered by a lack of structural and mutational data on the receptor. We ha...

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Main Authors: Jorissen, R. N., Epa, V. C., Treutlein, H. R., Garrett, T. P., Ward, C. W., Burgess, A. W.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2000
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144539/
https://ncbi.nlm.nih.gov/pubmed/10716183
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