The Schiff base complex of yeast 5-aminolaevulinic acid dehydratase with laevulinic acid.

The X-ray structure of the complex formed between yeast 5-aminolaevulinic acid dehydratase (ALAD) and the inhibitor laevulinic acid has been determined at 2.15 A resolution. The inhibitor binds by forming a Schiff base link with one of the two invariant lysines at the catalytic center: Lys263. It is...

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Hlavní autoři: Erskine, P. T., Newbold, R., Roper, J., Coker, A., Warren, M. J., Shoolingin-Jordan, P. M., Wood, S. P., Cooper, J. B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1999
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144351/
https://ncbi.nlm.nih.gov/pubmed/10386874
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