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A common mechanism for recombinant human NGF, BDNF, NT-3, and murine NGF slow unfolding.

The recombinant human nerve growth factor (hNGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin 4/5 (NT4/5), and murine NGF (mNGF) dimers all undergo rapid unfolding and dissociation to monomer in GdnHCl. Fluorescence spectroscopy, reversed-phase high-performance liqu...

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Detalhes bibliográficos
Main Authors: De Young, L. R., Schmelzer, C. H., Burton, L. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144210/
https://ncbi.nlm.nih.gov/pubmed/10595557
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