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Anatomy of protein pockets and cavities: measurement of binding site geometry and implications for ligand design.

Identification and size characterization of surface pockets and occluded cavities are initial steps in protein structure-based ligand design. A new program, CAST, for automatically locating and measuring protein pockets and cavities, is based on precise computational geometry methods, including alph...

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Bibliografski detalji
Glavni autori: Liang, J., Edelsbrunner, H., Woodward, C.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144175/
https://ncbi.nlm.nih.gov/pubmed/9761470
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