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Local water bridges and protein conformational stability.

Recent studies have pointed out the important role of local water structures in protein conformational stability. Here, we present an accurate and computationally effective way to estimate the free energy contribution of the simplest water structure motif--the water bridge. Based on the combination...

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Detalhes bibliográficos
Main Authors: Petukhov, M., Cregut, D., Soares, C. M., Serrano, L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144129/
https://ncbi.nlm.nih.gov/pubmed/10548043
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