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New evidence for the denaturant binding model.
Denaturation with guanidine hydrochloride (GdnHCl) or urea is one of the primary ways of measuring the conformational stability of proteins and comparing the stability of mutant proteins. Despite the widespread use of these two denaturants to provide quantitative data for the free energies of unfold...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
1999
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2144127/ https://ncbi.nlm.nih.gov/pubmed/10548055 |
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