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Backbone dynamics of the human CC chemokine eotaxin: fast motions, slow motions, and implications for receptor binding.

Eotaxin is a member of the chemokine family of about 40 proteins that induce cell migration. Eotaxin binds the CC chemokine receptor CCR3 that is highly expressed by eosinophils, and it is considered important in the pathology of chronic respiratory disorders such as asthma. The high resolution stru...

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Main Authors: Crump, M. P., Spyracopoulos, L., Lavigne, P., Kim, K. S., Clark-lewis, I., Sykes, B. D.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144122/
https://ncbi.nlm.nih.gov/pubmed/10548050
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