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On the non-respect of the thermodynamic cycle by DsbA variants.

The mechanism of the disulfide-bond forming enzyme DsbA depends on the very low pKa of a cysteine residue in its active-site and on the relative instability of the oxidized enzyme compared to the reduced one. A thermodynamic cycle has been used to correlate its redox properties to the difference in...

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Bibliografiske detaljer
Main Authors: Moutiez, M., Burova, T. V., Haertlé, T., Quéméneur, E.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144097/
https://ncbi.nlm.nih.gov/pubmed/10210189
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