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Mechanics and dynamics of B1 domain of protein G: role of packing and surface hydrophobic residues.

The structural organization of the B1 domain of streptococcal protein G (PGA) has been probed using molecular dynamics simulations, with a particular emphasis on the role of the solvent exposed Ile6 residue. In addition to the native protein (WT-PGA), three single-mutants (I6G-PGA, I6F-PGA, and I6T-...

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Autors principals: Ceruso, M. A., Amadei, A., Di Nola, A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144094/
https://ncbi.nlm.nih.gov/pubmed/10210193
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