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Turn scanning by site-directed mutagenesis: application to the protein folding problem using the intestinal fatty acid binding protein.

We have systematically mutated residues located in turns between beta-strands of the intestinal fatty acid binding protein (IFABP), and a glycine in a half turn, to valine and have examined the stability, refolding rate constants and ligand dissociation constants for each mutant protein. IFABP is an...

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Bibliografiske detaljer
Main Authors: Kim, K., Frieden, C.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144079/
https://ncbi.nlm.nih.gov/pubmed/10082380
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