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The equilibrium unfolding of Azotobacter vinelandii apoflavodoxin II occurs via a relatively stable folding intermediate.

A flavodoxin from Azotobacter vinelandii is chosen as a model system to study the folding of alpha/beta doubly wound proteins. The guanidinium hydrochloride induced unfolding of apoflavodoxin is demonstrated to be reversible. Apoflavodoxin thus can fold in the absence of the FMN cofactor. The unfold...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van Mierlo, C. P., van Dongen, W. M., Vergeldt, F., van Berkel, W. J., Steensma, E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143863/
https://ncbi.nlm.nih.gov/pubmed/9827999
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