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Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.

Two closely related bacterial toxins, heat-labile enterotoxin (LT-I) and cholera toxin (CT), not only invoke a toxic activity that affects many victims worldwide but also contain a beneficial mucosal adjuvant activity that significantly enhances the potency of vaccines in general. For the purpose of...

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Autors principals: van den Akker, F., Pizza, M., Rappuoli, R., Hol, W. G.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143616/
https://ncbi.nlm.nih.gov/pubmed/9416617
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