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Posttranslational processing of recombinant human interferon-gamma in animal expression systems.

We have characterized the heterogeneity of recombinant human interferon-gamma (IFN-gamma) produced by three expression systems: Chinese hamster ovary cells, the mammary gland of transgenic mice, and baculovirus-infected Spodopera frugiperda (Sf9) insect cells. Analyses of whole IFN-gamma proteins by...

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Bibliographic Details
Main Authors: James, D. C., Goldman, M. H., Hoare, M., Jenkins, N., Oliver, R. W., Green, B. N., Freedman, R. B.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1996
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143336/
https://ncbi.nlm.nih.gov/pubmed/8745411
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