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A fast conformational search strategy for finding low energy structures of model proteins.

We describe a new computer algorithm for finding low-energy conformations of proteins. It is a chain-growth method that uses a heuristic bias function to help assemble a hydrophobic core. We call it the Core-directed chain Growth method (CG). We test the CG method on several well-known literature ex...

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Detalhes bibliográficos
Main Authors: Beutler, T. C., Dill, K. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143263/
https://ncbi.nlm.nih.gov/pubmed/8897604
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