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UME6, a negative regulator of meiosis in Saccharomyces cerevisiae, contains a C-terminal Zn2Cys6 binuclear cluster that binds the URS1 DNA sequence in a zinc-dependent manner.

UME6 is a protein of 836 amino acids from Saccharomyces cerevisiae that acts as a repressor and activator of several early meiotic genes. UME6 contains, near the C-terminus, the amino acid sequence-771C-X2-C-X6-C-X6-C-X2-C-X6-C-, in which the spacings of the six Cys residues are identical to those f...

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Autors principals: Anderson, S. F., Steber, C. M., Esposito, R. E., Coleman, J. E.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143208/
https://ncbi.nlm.nih.gov/pubmed/8528081
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