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The role of aspartate-235 in the binding of cations to an artificial cavity at the radical site of cytochrome c peroxidase.

The activated state of cytochrome c peroxidase, compound ES, contains a cation radical on the Trp-191 side chain. We recently reported that replacing this tryptophan with glycine creates a buried cavity at the active site that contains ordered solvent and that will specifically bind substituted imid...

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Main Authors: Fitzgerald, M. M., Trester, M. L., Jensen, G. M., McRee, D. E., Goodin, D. B.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143207/
https://ncbi.nlm.nih.gov/pubmed/8528082
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