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Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry.

The structure of the potassium channel blocker agitoxin 2 was solved by solution NMR methods. The structure consists of a triple-stranded antiparallel beta-sheet and a single helix covering one face of the beta-sheet. The cysteine side chains connecting the beta-sheet and the helix form the core of...

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Bibliographic Details
Main Authors: Krezel, A. M., Kasibhatla, C., Hidalgo, P., MacKinnon, R., Wagner, G.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143198/
https://ncbi.nlm.nih.gov/pubmed/8520473
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