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Slow-folding kinetics of ribonuclease-A by volume change and circular dichroism: evidence for two independent reactions.

The slow refolding of guanidine-HCl-denatured ribonuclease-A was studied by volume change and by kinetic CD at 222 and 276 nm. Dilatometric measurements revealed that on refolding there is a fast volume change of +232 mL/mol of protein. This is followed by a very slow nonexponential change that take...

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Hlavní autoři: Ybe, J. A., Kahn, P. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142864/
https://ncbi.nlm.nih.gov/pubmed/8003982
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