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A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides.

A common structural motif consisting of a cystine knot and a small triple-stranded beta-sheet has been defined from comparison of the 3-dimensional structures of the polypeptides omega-conotoxin GVIA (Conus geographus), kalata BI (Oldenlandia affinis DC), and CMTI-I (Curcurbita maxima). These 3 poly...

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Bibliografiske detaljer
Main Authors: Pallaghy, P. K., Nielsen, K. J., Craik, D. J., Norton, R. S.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142598/
https://ncbi.nlm.nih.gov/pubmed/7849598
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