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Binding of amino acid side chains to preformed cavities: interaction of serine proteinases with turkey ovomucoid third domains with coded and noncoded P1 residues.

In the association of serine proteinases with their cognate substrates and inhibitors an important interaction is the fitting of the P1 side chain of the substrate or inhibitor into a preformed cavity of the enzyme called the S1 pocket. In turkey ovomucoid third domain, which is a canonical protein...

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Detalhes bibliográficos
Main Authors: Bigler, T. L., Lu, W., Park, S. J., Tashiro, M., Wieczorek, M., Wynn, R., Laskowski, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142496/
https://ncbi.nlm.nih.gov/pubmed/8495199
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