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Structural investigation of catalytically modified F120L and F120Y semisynthetic ribonucleases.

The structures of two catalytically modified semisynthetic RNases obtained by replacing phenylalanine 120 with leucine and tyrosine have been determined and refined at a resolution of 2.0 A (R = 0.161 and 0.184, respectively). These structures have been compared with the refined 1.8-A structure (R =...

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Detalhes bibliográficos
Main Authors: deMel, V. S., Doscher, M. S., Glinn, M. A., Martin, P. D., Ram, M. L., Edwards, B. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142485/
https://ncbi.nlm.nih.gov/pubmed/8142897
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