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Prolyl isomerases catalyze antibody folding in vitro.

Some slow-folding phases in the in vitro refolding of proteins originate from the isomerization of prolyl-peptide bonds, which can be accelerated by a class of enzymes called prolyl isomerases (PPIs). We used the in vitro folding of an antibody Fab fragment as a model system to study the effect of P...

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Autori principali: Lilie, H., Lang, K., Rudolph, R., Buchner, J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142458/
https://ncbi.nlm.nih.gov/pubmed/8104614
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