Recombinant human erythropoietin (rHuEPO): cross-linking with disuccinimidyl esters and identification of the interfacing domains in EPO.

Several amino groups of recombinant human erythropoietin are selectively cross-linked by specific cross-linkers including disuccinimidyl suberate or dithiobis(succinimidyl propionate). Intramolecular cross-linkings are obtained without significant change of the protein conformation using appropriate...

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Bibliographic Details
Main Authors: Haniu, M., Narhi, L. O., Arakawa, T., Elliott, S., Rohde, M. F.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142457/
https://ncbi.nlm.nih.gov/pubmed/8401229
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