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In vivo formation of active aspartate transcarbamoylase from complementing fragments of the catalytic polypeptide chains.

Despite the complexity of Escherichia coli aspartate transcarbamoylase (ATCase), composed of 12 polypeptide chains organized as two catalytic (C) trimers and three regulatory (R) dimers, it is possible to form active stable enzyme in vivo even with fragmented catalytic (c) chains. Based on the obser...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Y. R., Schachman, H. K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142402/
https://ncbi.nlm.nih.gov/pubmed/8318886
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