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Mapping antibody binding sites on cytochrome c with synthetic peptides: are results representative of the antigenic structure of proteins?

Crystallographic work on antigen-antibody complexes has revealed that extensive surface areas of proteins may interact with antibodies. On the other hand, most experimental approaches to locate and define antigenic determinants of protein antigens rely on the linear sequence of the polypeptide chain...

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Détails bibliographiques
Auteurs principaux: Schwab, C., Twardek, A., Lo, T. P., Brayer, G. D., Bosshard, H. R.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142349/
https://ncbi.nlm.nih.gov/pubmed/7680266
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