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P22 Arc repressor: enhanced expression of unstable mutants by addition of polar C-terminal sequences.

Many mutant variants of the P22 Arc repressor are subject to intracellular proteolysis in Escherichia coli, which precludes their expression at levels sufficient for purification and subsequent biochemical characterization. Here we examine the effects of several different C-terminal extension sequen...

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Bibliographic Details
Main Authors: Milla, M. E., Brown, B. M., Sauer, R. T.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142328/
https://ncbi.nlm.nih.gov/pubmed/8298465
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